Speaking of food, the city serves up an abundance of spice and flavor, with an estimated 50-plus regional cuisines represented throughout the vibrant street food scene, along with burgeoning fine-dining offerings. Head over to Blanco Colima, operating out of a 20th-century mansion, or to Pujol, among the top 50 restaurants in the world, where chef Enrique Olvera elevates Mexican gastronomy with unique techniques and mouthwatering dishes.

Standing at nearly 7,400 feet above sea level and situated in a valley surrounded by volcanoes, Mexico City offers an array of activities to satisfy any traveler. Past and present combine in the 10-acre Historic Center, where museums, cathedrals and temples reveal a storied past, while Zócalo, the main public square (and second-largest in the world after Moscow’s Red Square), buzzes with constant action.

More than 150 museums in the city celebrate Latin American culture, history, science and more. The most popular spots include Soumaya Museum and Palacio de Bellas Artes, but be sure to visit Dolores Olmedo Museum, housing a large collection of work by famed artists Frida Kahlo and Diego Rivera.

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Mexico boasts more UNESCO World Heritage sites than any other country in the Americas, and visitors to Mexico City won’t want to miss the ancient archaeological site of Teotihuacán, just 45 minutes northeast of the capital. The monumental Temple of Quetzalcóatl and the Pyramids of the Sun and the Moon line Avenue of the Dead, serving as focal points for the ancient city’s layout and marvelous to see.

On the vibrant cobblestone streets of Mexico City’s Coyoacán borough, the combination of bustling markets and colonial churches transports visitors back in time. Grab a bite of classic Mexican cuisine at Los Danzantes and take a short walk to La Casa Azul (Blue House), the former home of Mexican icon Frida Kahlo. In the south of Mexico City, travel to Xochimilco, where a network of canals leads you to chinampas, or floating gardens. Take a ride on the trajineras, brightly decorated flat-bottom boats, to roam the canals and purchase drinks and snacks on the waterways.