Roundabout Weekender Tote 
The Alexis Drake Roundabout Weekender Tote offers a sleek combination of style, function and craftsmanship. At 14.5 inches by 27 inches by 10 inches, the Roundabout’s impressive capacity can support any weekend, long or short, without sacrificing its sleek silhouette. Meticulously handcrafted from full-grain cow and bison leathers sourced within the United States and lined with woven canvas, four large pockets keep the sizable interior organized, while reinforced handles and an optional shoulder strap provide superior support. Available in a variety of striking, limited-run color combinations, with customizable details. $598.

© Tusk

Troy Wave Everyday Duffel 
The Troy Wave Everyday Duffel from Tusk is a testament to understated sophistication. Handcrafted from Italian calfskin leather in a handsome chocolate tone, the supple texture develops a unique patina over time for increasing refinement with each journey. At 15 inches by 11 inches by 8 inches, the versatile Troy smartly blurs the line between an oversized everyday bag and a respectable duffel for quick weekend getaways. And with smart interior organization including a zipper pocket and two slide pockets, it easily supports either. Includes a detachable shoulder strap and dust bag. $428.

© By Christopher King

Duffle 53cm Leather
The Duffle 53cm Leather bag by Christopher King exemplifies superior Italian craftsmanship and luxury. Handcrafted in Italy from premium, durable leather, the exterior features solid brass hardware coated in pure white gold and is embellished with the brand’s signature gold-plated crowns. Double zipper closures secure an interior lined with blue suede and containing two additional zippers for organized storage. An adjustable strap with plush diamond-stitched padding makes shoulder carry considerably more enjoyable for a bag combining total functionality with timeless elegance. $3,600.

© Patricia Nash Designs

Mandara Overnighter Duffel
Meticulously crafted from patina-coated linen canvas, the water-resistant Mandara Overnighter Duffel from Patricia Nash features an intricate European map design for those with a penchant for vintage-inspired travel nostalgia. Key touches such as stud detailing and rich leather trim enhance the bag’s visual appeal while reinforcing its structure as it stands up to any adventure. The generous 20.5-inch by 11.5-inch by 7-inch sizing provides ample space for weekend getaways, and the convenient luggage sleeve supports maximum airport efficiency for carry-on use. $249.